. Professor, Department of Otolaryngology - Head and Neck Surgery; . The P4 lab is located in a new developing zone about one hour car ride from the current institute location in central Wuhan city. The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric . Moreover, co-evolution between plants and microbes is greatly impacted by ongoing climate change. is author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. Affiliations. Cambridge, Massachusetts. research American Heart Association grant will support undergraduates interested in pursuing cardiovascular research Jan 04, 2023. research Virginia Tech scientist uncovers possible neural link between early life trauma and binge-eating disorder Dec 12, 2022. research State iTHRIV partnership awards $200,000 in pilot funds Dec 05, 2022. Postdoctoral Fellow, Laboratory of Steven McCarroll, Harvard Medical School and Broad Institute of MIT and Harvard. Prof. Gong's research group focuses on the design, synthesis/fabrication, and characterization of novel materials and devices. Massachusetts Institute of Technology The Chen Lab. We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders. The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Background and aimsAs a result of increasing numbers of studies most recently, mitophagy plays a vital function in the genesis of cancer. Phone. Many of their ongoing projects are multidisciplinary, bridging engineering with materials science, chemistry, and life sciences. Then she was a postdoctoral research scientist in the laboratory of Richard Axel at Columbia University. Feng Laboratory McGovern Institute For Brain Research 43 Vassar Street, Office: 46-3133 Cambridge, Massachusetts 02139 Phone: (617) 715-4920 Website: fenglaboratory.org. The Broad Institute of MIT & Harvard is looking for a Research Associate II to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research. Shawn has a broad range of experience: mechanical and electrical system modeling and analysis; data sensing and sensor placement; signal processing; machine learning and artificial intelligence; machine defect classification and level evaluation; machine life prognosis; multi scale modeling; traditional and . The successful candidate will join a multidisciplinary group and perform cutting-edge basic and/or translational research on the molecular, cellular and . The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric Research. The scope will include integration with other internal and external genomics datasets. . Lab or Bio Link: Lihu Kolton Email: Postdoc 1983-1986: Patent Attorney, Ehrlich & Fenster: Website: Flora Katz . Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. Pasadena, CA 91125. (1st class honors) from Oxford University and obtained his medical degree and training at London University. Senior investigator, Chief of Synaptic Functions Section, NINDS, NIH. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. His Ph.D. thesis was completed at Harvard Medical School in the lab of Michael Greenberg. Just another site. M Sheng, S Smiga, A Bulfone, . From 2001 to 2008, Sheng was the Menicon Professor of Neuroscience at MIT, as well as an investigator of the Howard Hughes Medical Institute. BBD has a multidisciplinary technical portfolio that includes genomic measurements, synthetic biology, regenerative medicine and advanced therapies, biomaterials, diagnostics, and complex microbial . Meet our members, staff scientists, fellows and other Broadies. Posted: December 20, 2022. Sheng Gong currently works at the Department of Materials Science & Engineering, Massachusetts Institute of Technology. The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric. To combat the COVID-19 pandemic, nonpharmaceutical interventions (NPI) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARI).Etiologically diagnostic data from 142 559 cases with ARIs, who were tested for eight . Mark Inman, MBA COO and Administrator . Chemical biology and therapeutics science, Genome regulation, cellular circuitry, and epigenomics, Merkin Institute for Transformative Technologies in Healthcare, Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Several pre-existing RSV lineages powered the 2022 surge, Blood stem cells are susceptible to ferroptosis, a type of cell death, Rare genetic variants can reveal much about disease biology, Researchers map brain cell changes in Alzheimers disease. . Email. Morgan Sheng Core Institute Member, Broad Institute of MIT and Harvard Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute Professor of Neuroscience, Department of Brain and Cognitive Sciences Affiliate Member, The Picower Institute for Learning and Memory Affiliate Member, McGovern Institute for Brain Research The four magnified images on the right show how the cell takes up the treatment across a span of 30 seconds. Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. At Genentechhe built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. Blainey Lab Golub Lab Hung Lab Lander Lab Liu Lab Regev Lab Schreiber Lab Sellers Lab Xavier Lab Zhang Lab Institute Member labs Eric Alm, MIT Paola Arlotta, Harvard Picower Professor of Biology and Neuroscience; Director, RIKEN-MIT Laboratory for Neural Circuit Genetics. In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both the McGovern Institute for Brain Research and the Picower Institute for Learning and Memory. (1st class honors) from Oxford University and obtained his medical degree and training at London University. Broad-spectrum disease resistance conferred by expression of the Pseudomonas syringae hrmA gene in plants (2001) Qingshun Li, Songhai Shen, Arthur Hunt and Sheng Yang He. SPANGLER LAB. He is an associate member of the Broad Institute. Minneapolis, MN +1 location. Sheng completed his medical training and a residency in general medicine in London, UK. The Elowitz lab is committed to creating an inclusive, diverse, and supportive environment, and we encourage postdoc applications from groups historically under-represented in science. Full-Time. Find our contact information, directions to our buildings, and directory. See Adata Technology 's products and customers Thousands of companies like you use Panjiva to research suppliers and competitors. Basic laboratory methods of molecular cell biology, imaging, and/or electrophysiology, Self-motivation and rigorousness in experimental research, Excellent communication skills (written and oral), Ability to work independently and interact cooperatively with others, Expertise in computational/bioinformatics approaches to biological problems, Experience of data-rich experimental techniques, such as single cell RNAseq, ATACseq, MS proteomics, functional genomic screens, high content imaging. Check out this video for a look into our community! The location will be the new campus for the entire institute in the near future (a lot of construction is going on right now). BBD has a multidisciplinary technical portfolio that includes genomic measurements, synthetic biology, regenerative medicine and advanced therapies, biomaterials, diagnostics . From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. Professor of Biology; Core Member, Broad Institute; Investigator, Howard Hughes Medical Institute. He received his PhD in Pharmacodymamics (with a focus onNeuroscience) from University of Lingling Yang is a research scientist I at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, working under the direction of Jen Q. Pan. Raozhou Lin is a molecular neuroscientist with a keen interest in understanding the causes for neuropsychiatric diseases. All Rights Reserved. Neurobiologist and drug developer returns to academia to help guide the Broads psychiatric research. Our group aims to redesign existing proteins and engineer new proteins that overcome these limitations. Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, 518052 P. R. China Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, 999077 . Her Juanchi is an electrophysiologist and cell biologist with a particular interest in the regulation of ion channels and how this understanding can be harnessed for potential disease interventions. Researchers in the Sheng . Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, Computational Associate II, Stanley Center for Psychiatric Research, Title: Computational Associate II, Stanley Center for Psychiatric Research. - Analyze large RNA-Seq datasets to profile transcriptomes from different brain regions at different ages and interpret results to derive important biological insights into these models. All Broad employees, regardless of work location, must be fully vaccinated for COVID-19 by Tuesday, October 12, 2021. Find us on Twitter. The position will provide an opportunity to become a part of the computational biology community at the Broad Institute. As the Director for Translational Neurobiology at Stanley Center, Dr. Pan aspires to translate the understanding of the genetics and biology of psychiatric and neurological illnesses to novel therapeutics for severe mental illnesses. Lab Website molbiolabs.princeton.edu/cristea ; 3 NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen . The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. Dr. Fei Chen, a current Broad fellow and co-inventor of expansion microscopy, is building a lab at the Broad Institute that is focused on developing methods for studying differences in genome structure and mRNA expression. Get email updates for new Research Scientist jobs in United States. $44,832 - $58,874 47% of jobs The average salary is $71,237 a year $58,875 - $72,918 18% of jobs $78,320 is the 75th percentile. Sheng laboratory focuses on mechanisms regulating axonal transport that is essential for the maintenance of synaptic function and axonal homeostasis. Currently, the Sheng lab focuses on three areas of research: Immune response to infection and vaccination: We develop computational methods to study immune responses of humans and animal models. Dr. Sheng received the 2021 Dr. Francisco S. Sy Award for Excellence in Mentorship at HHS. I am excited to return to academia and establish a research lab at the Broad, said Sheng. Broad Institute. In back-fill mining, how to rapidly increase the concentration of tailings is an important problem facing mining engineers. The role will often involve rapid prototyping in support of a dynamic, fast-moving experimental program; it is focused on molecular biology applications relevant to investigation of brain function and psychiatric illness. The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments. Biological products exc.diagnostic Umbilical cord blood stem cells and collection, storage, should be the technical services and research and development) Borislav Dejanovic, PhD (Staff Scientist/ Group Leader, Broad Institute), Sarah Wade (Research Associate, Broad Institute), Core Institute Member, Broad Institute of MIT and Harvard, Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Office: Broad Institute, 75 Ames St. Room 9023. Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research. The long-term goal of the laboratory is to decipher mechanisms (1) boosting axonal and synaptic energy metabolism and (2) enhancing autophagy-lysosomal function for efficient clearance of dysfunctional organelles and aggregated proteins that are associated with major neurodegenerative diseases. AY Hung, M Sheng. Mechanisms regulating axonal organelle transport in healthy and diseased neurons. Sheng is a fellow of the Royal Society (UK), a fellow of the Academy of Medical Sciences (UK), a fellow of the American Association for the Advancement of Science, and honorary fellow of Corpus Christi College, Oxford. Featuring speakers from the Wilson, Tonegawa, and Miller labs.. Moderated by BU Professor and Tonegawa lab alumnus Steve Ramirez. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology . in chemistry with honors from Caltech in 1999, and a . Research Areas . Laboratory Technician 1,190 job openings. a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. Click the link in the email we sent to to verify your email address and activate your job alert. This candidate will collaborate with biologists and geneticists to perform various . Requests for exemption for medical or sincerely held religious beliefs will be considered. Nature neuroscience 12 (4), 428-437, 2009. . The Sheng lab uses interdisciplinary approaches to elucidate the mechanisms of humoral immune response to infection and to understand the role of B cells in autoimmunity. University of California, Berkeley, and her Ph.D. from Caltech. Published in NANO Letters, the study was led by Zhi Sheng and Deborah . The labhas used a broad range of approaches to tackle these problems, notably the development of neuronal cultures from adult disease mouse models and live imaging of various organelle transport. Shengs molecular studies of the structure and function of synapses (the communication junctions between brain cells) while at MGH and MIT have enhanced our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, neurodevelopmental disorders, and dementia. In Situ Biology . The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. From 2001 to 2008, Sheng was the Menicon Professor of Neuroscience at MIT, as well as an investigator of the Howard Hughes Medical Institute. He has served on the editorial boards of Neuron, Journal of Neuroscience, and Current Opinions in Neurobiology. Learn about breakthroughs from Broad scientists. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the. In 2020 she graduated from Rutgers University with her MS in Biomedical Science with a concentration in Neuroscience. . is working in Medical laboratories activities. Categories . The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). 46-5285. . gu_hongcang@hotmail.com. 617-714-7021. The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: / b r o d /, pronunciation respelling: BROHD), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it . Here, we report a single-molecule approach capable of . +1 415 734-2717. As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to shape the centers scientific vision and direction, and oversee the centers efforts to develop therapeutics for schizophrenia and other serious mental illnesses. The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region. Job title Senior Technical Lead. Cambridge, MA 02139 The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Abstract. Zizhang Sheng is an associated research scientist in the Honig-Shapiro labs. However, research on the predictive potential and clinical importance of mitophagy-related genes (MRGs) in hepatocellular carcinoma (HCC) is currently lacking. Dr. Sheng was elected to AAAS Fellow in 2016 and ASCB fellow in 2017 for his contributions to the field of axonal transport of mitochondria and endolysosomes in maintenance of neuronal homeostasis and synaptic function in health and diseases. Associate Investigator, Broad Institute of Harvard/MIT Investigator, HHMI. sheng.ding@gladstone.ucsf.edu. 2018 Feb 5;217(2):459-472. doi: 10.1083/jcb.201709069. Check out this video for a look into our community! Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations. During his Ph.D., he . sweet things to write in a baby book. Research Scientist I - Therapeutics Group - Sheng Lab. Zhe Ji, Ph.D. Assistant Professor Postdoc in Systems Biology, Harvard Medical School Postdoc in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in RNA Genomics, Rutgers University E Core Institute Members have their primary laboratories in the Broad Institute facilities. EEO is The Law - click here for more information, Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled. Merkin Building Sheng does research in Physical Chemistry, Solid-state Chemistry and Solid . Sign in to create your job alert for Research Scientist jobs in United States. These studies have led to the identification of three motor adaptor and anchoring proteins (syntaphilin, Snapin, and syntabulin) that regulate axonal transport of mitochondria, endo-lysosomes, autophagosomes, and synaptic cargoes. Our researchers use their expertise in creating, adapting, and applying a variety of technologies to enable science here and beyond. Identified telomerase isoforms by integrating NGS and RACE data: Designed and performed experiments (RACE) and sequence analyses (bash). The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease. Massachusetts Institute of Technology 43 Vassar Street, Bldg. Compositions and Methods for Conversion of Aldehydes to Alkanes (2011) Weiqing Zeng and Sheng Yang He. Lab Administrator. 415 Main St. Sheng is an elected Fellow of the Royal Society (UK), the Academy of Medical Sciences (UK), and the AAAS. I am looking forward to joining this community of innovative researchers and applying my expertise to discover novel therapies and improve the lives of people with mental illness.. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. He obtained his Ph.D. in biological engineering from the Massachusetts Institute of Technology in 2016. Current Youth Development Coordinator at David Scott School - Brotherhood of St Laurence, responsible for developing and creating industry immersion events with the desire of expanding students' future horizons by facilitating career development programs and providing vocational guidance for senior (Year12) students in the preparation for post-school transition. Fellow of the Royal Society (FRS), London, UK (elected 2007), Fellow of the Academy of Medical Sciences (UK) (elected 2009), Honorary Fellow, Corpus Christi College, Oxford (elected 2010), Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimers disease, Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies, Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation, TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia, Researchers map brain cell changes in Alzheimers disease. We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders. This position in the Stanley Center for Psychiatric Research involves bioinformatics analysis in areas such as transcriptomics, neurophysiology, and behavior. Registered Nurse. Massachusetts Institute of Technology. His research at Genentech focused on human genetics and pathogenic mechanisms of neurodegenerative disease, particularly Alzheimers and Parkinsons diseases. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. 415 Main St. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental . A past recipient of the Fondation Ipsen Prize in Neuronal Plasticity and the Young Investigator Award of the Society for Neuroscience, Sheng received a B.A. Full-time. Software Engineer. This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. Sheng J, Zhang W, Hassan A, Gan J, Soares A, Geng S, Ren Y, Huang Z. Hydrogen Bond Formation between the Naturally Modified Nucleobase and Phosphate Backbone. This candidate will collaborate with biologists and geneticists to perform various analysis including transcriptomics and proteomics analysis, pathway analysis and biological interpretations.